I24I (p.Ile24Ile) variant of MDM4 (Protein Mdm4)
I24I (p.Ile24Ile) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
I24I (p.Ile24Ile) variant details
- p.Ile24Ile
- rs2102314635
- gnomAD 1-204525590-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.433
- CADD 8.56
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.103
- Literature evidence available