I19M (p.Ile19Met) variant of MDM4 (Protein Mdm4)
I19M (p.Ile19Met) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, and structural context.
I19M (p.Ile19Met) variant details
- p.Ile19Met
- cosmic curated COSV10091
- 1000Genomes rs148900701
- ESP rs148900701
- ExAC rs148900701
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.03
- CADD 21.00
- PolyPhen-2 0.12
- SIFT 0.03
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.355