G22V (p.Gly22Val) variant of MDM4 (Protein Mdm4)
G22V (p.Gly22Val) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G22V (p.Gly22Val) variant details
- p.Gly22Val
- TOPMed rs1660048593
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- CADD 4.19
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.881