G22T (p.Gly22Thr) variant of MDM4 (Protein Mdm4)
G22T (p.Gly22Thr) in MDM4 (Protein Mdm4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G22T (p.Gly22Thr) variant details
- p.Gly22Thr
- gnomAD 1-204525581-TGG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.307
- CADD 32.00
- Population evidence available
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.881
- Literature evidence available