G22R (p.Gly22Arg) variant of MDM4 (Protein Mdm4)
G22R (p.Gly22Arg) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- ExAC rs748876366
- gnomAD rs748876366
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.10
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.28
- Population evidence available
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.881