D14G (p.Asp14Gly) variant of MDM4 (Protein Mdm4)
D14G (p.Asp14Gly) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, and structural context.
D14G (p.Asp14Gly) variant details
- p.Asp14Gly
- Ensembl rs1660044128
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.02
- CADD 20.30
- PolyPhen-2 0.02
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.0953