A8G (p.Ala8Gly) variant of MDM4 (Protein Mdm4)
A8G (p.Ala8Gly) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A8G (p.Ala8Gly) variant details
- p.Ala8Gly
- TOPMed rs1660043113
- gnomAD rs1660043113
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.09
- CADD 22.90
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.858