Y56Y (p.Tyr56Tyr) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
Y56Y (p.Tyr56Tyr) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
Y56Y (p.Tyr56Tyr) variant details
- p.Tyr56Tyr
- rs997464909
- gnomAD 12-68813616-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0964
- CADD 2.22
- Most common in the Amish population (allele frequency 0.0011)
- Structural context available
- Literature evidence available