R29R (p.Arg29Arg) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
R29R (p.Arg29Arg) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R29R (p.Arg29Arg) variant details
- p.Arg29Arg
- gnomAD 12-68808486-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.3
- CADD 5.50
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- MDM2 Zinc finger, RanBP2-type domain domainome 1.0: score -0.499
- Literature evidence available