Q24Q (p.Gln24Gln) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
Q24Q (p.Gln24Gln) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q24Q (p.Gln24Gln) variant details
- p.Gln24Gln
- rs1880647399
- gnomAD 12-68809265-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.464
- CADD 14.50
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- MDM2 Zinc finger, RanBP2-type domain domainome 1.0: score -0.945
- Literature evidence available