P32T (p.Pro32Thr) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
P32T (p.Pro32Thr) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
P32T (p.Pro32Thr) variant details
- p.Pro32Thr
- gnomAD 12-68813566-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.24
- CADD 23.60
- PolyPhen-2 0.97
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available