L57S (p.Leu57Ser) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
L57S (p.Leu57Ser) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L57S (p.Leu57Ser) variant details
- p.Leu57Ser
- gnomAD 12-68815647-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- CADD 9.06
- Population evidence available
- Structural context available
- Literature evidence available