K36N (p.Lys36Asn) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
K36N (p.Lys36Asn) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K36N (p.Lys36Asn) variant details
- p.Lys36Asn
- gnomAD 12-68813565-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.31
- CADD 23.00
- PolyPhen-2 0.80
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available