I74T (p.Ile74Thr) variant of MDM2 (E3 ubiquitin-protein ligase Mdm2)
I74T (p.Ile74Thr) in MDM2 (E3 ubiquitin-protein ligase Mdm2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
I74T (p.Ile74Thr) variant details
- p.Ile74Thr
- gnomAD 12-68815683-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- CADD 5.56
- Population evidence available
- Structural context available
- Literature evidence available