Y87C (p.Tyr87Cys) variant of MCM6 (Q14566)
Y87C (p.Tyr87Cys) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
Y87C (p.Tyr87Cys) variant details
- p.Tyr87Cys
- gnomAD rs1255593627
- Missense
- Variant Prioritization Score for Impact Estimate 0.633
- REVEL 0.61
- CADD 28.90
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available