Y84S (p.Tyr84Ser) variant of MCM6 (Q14566)
Y84S (p.Tyr84Ser) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
Y84S (p.Tyr84Ser) variant details
- p.Tyr84Ser
- ExAC rs771924466
- TOPMed rs771924466
- gnomAD rs771924466
- Missense
- Variant Prioritization Score for Impact Estimate 0.63
- REVEL 0.60
- CADD 28.80
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available