V98L (p.Val98Leu) variant of MCM6 (Q14566)
V98L (p.Val98Leu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
V98L (p.Val98Leu) variant details
- p.Val98Leu
- ESP rs375834809
- ExAC rs375834809
- TOPMed rs375834809
- gnomAD rs375834809
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.09
- CADD 22.40
- PolyPhen-2 0.03
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available