V98I (p.Val98Ile) variant of MCM6 (Q14566)
V98I (p.Val98Ile) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V98I (p.Val98Ile) variant details
- p.Val98Ile
- ESP rs375834809
- ExAC rs375834809
- TOPMed rs375834809
- gnomAD rs375834809
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.07
- CADD 20.80
- PolyPhen-2 0.03
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available