V63G (p.Val63Gly) variant of MCM6 (Q14566)
V63G (p.Val63Gly) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
V63G (p.Val63Gly) variant details
- p.Val63Gly
- ExAC rs758646175
- gnomAD rs758646175
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.70
- CADD 28.20
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available