V147I (p.Val147Ile) variant of MCM6 (Q14566)
V147I (p.Val147Ile) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V147I (p.Val147Ile) variant details
- p.Val147Ile
- ExAC rs754390262
- TOPMed rs754390262
- gnomAD rs754390262
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.18
- CADD 23.30
- PolyPhen-2 0.33
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available