V147F (p.Val147Phe) variant of MCM6 (Q14566)
V147F (p.Val147Phe) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
V147F (p.Val147Phe) variant details
- p.Val147Phe
- ExAC rs754390262
- TOPMed rs754390262
- gnomAD rs754390262
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.37
- CADD 25.90
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available