T96I (p.Thr96Ile) variant of MCM6 (Q14566)
T96I (p.Thr96Ile) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T96I (p.Thr96Ile) variant details
- p.Thr96Ile
- TOPMed rs1680177033
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.04
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available