S76F (p.Ser76Phe) variant of MCM6 (Q14566)
S76F (p.Ser76Phe) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
S76F (p.Ser76Phe) variant details
- p.Ser76Phe
- gnomAD rs201423668
- Missense
- Variant Prioritization Score for Impact Estimate 0.535
- REVEL 0.35
- CADD 27.90
- PolyPhen-2 0.62
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00013)
- Structural context available