R85S (p.Arg85Ser) variant of MCM6 (Q14566)
R85S (p.Arg85Ser) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R85S (p.Arg85Ser) variant details
- p.Arg85Ser
- ExAC rs776797839
- gnomAD rs776797839
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.45
- CADD 26.00
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available