R58G (p.Arg58Gly) variant of MCM6 (Q14566)
R58G (p.Arg58Gly) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R58G (p.Arg58Gly) variant details
- p.Arg58Gly
- ExAC rs751992613
- gnomAD rs751992613
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.31
- CADD 25.20
- PolyPhen-2 0.81
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available