R101L (p.Arg101Leu) variant of MCM6 (Q14566)
R101L (p.Arg101Leu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R101L (p.Arg101Leu) variant details
- p.Arg101Leu
- 1000Genomes rs566522057
- ExAC rs566522057
- TOPMed rs566522057
- gnomAD rs566522057
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.11
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available