R101H (p.Arg101His) variant of MCM6 (Q14566)
R101H (p.Arg101His) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R101H (p.Arg101His) variant details
- p.Arg101His
- 1000Genomes rs566522057
- ExAC rs566522057
- TOPMed rs566522057
- gnomAD rs566522057
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.07
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available