R101G (p.Arg101Gly) variant of MCM6 (Q14566)
R101G (p.Arg101Gly) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R101G (p.Arg101Gly) variant details
- p.Arg101Gly
- ExAC rs767037709
- TOPMed rs767037709
- gnomAD rs767037709
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.14
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available