Q115R (p.Gln115Arg) variant of MCM6 (Q14566)
Q115R (p.Gln115Arg) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
Q115R (p.Gln115Arg) variant details
- p.Gln115Arg
- gnomAD rs1680175930
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.08
- CADD 22.20
- PolyPhen-2 0.04
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available