P9Q (p.Pro9Gln) variant of MCM6 (Q14566)
P9Q (p.Pro9Gln) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
P9Q (p.Pro9Gln) variant details
- p.Pro9Gln
- ExAC rs779145315
- TOPMed rs779145315
- gnomAD rs779145315
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.08
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available