P9L (p.Pro9Leu) variant of MCM6 (Q14566)
P9L (p.Pro9Leu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P9L (p.Pro9Leu) variant details
- p.Pro9Leu
- ExAC rs779145315
- TOPMed rs779145315
- gnomAD rs779145315
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.06
- CADD 23.70
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available