N72S (p.Asn72Ser) variant of MCM6 (Q14566)
N72S (p.Asn72Ser) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
N72S (p.Asn72Ser) variant details
- p.Asn72Ser
- TOPMed rs1680224928
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.12
- CADD 22.20
- PolyPhen-2 0.08
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available