N59K (p.Asn59Lys) variant of MCM6 (Q14566)
N59K (p.Asn59Lys) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N59K (p.Asn59Lys) variant details
- p.Asn59Lys
- Ensembl rs1558764553
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.18
- CADD 24.60
- PolyPhen-2 0.69
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available