L3V (p.Leu3Val) variant of MCM6 (Q14566)
L3V (p.Leu3Val) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L3V (p.Leu3Val) variant details
- p.Leu3Val
- ExAC rs769922920
- gnomAD rs769922920
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.09
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available