K99E (p.Lys99Glu) variant of MCM6 (Q14566)
K99E (p.Lys99Glu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K99E (p.Lys99Glu) variant details
- p.Lys99Glu
- TOPMed rs1680176856
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.14
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available