K28N (p.Lys28Asn) variant of MCM6 (Q14566)
K28N (p.Lys28Asn) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K28N (p.Lys28Asn) variant details
- p.Lys28Asn
- ExAC rs773891158
- TOPMed rs773891158
- gnomAD rs773891158
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.12
- CADD 22.50
- PolyPhen-2 0.10
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available