K122R (p.Lys122Arg) variant of MCM6 (Q14566)
K122R (p.Lys122Arg) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K122R (p.Lys122Arg) variant details
- p.Lys122Arg
- TOPMed rs1680175653
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.07
- CADD 22.30
- PolyPhen-2 0.11
- SIFT 0.41
- Population evidence available
- Structural context available