K102R (p.Lys102Arg) variant of MCM6 (Q14566)
K102R (p.Lys102Arg) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K102R (p.Lys102Arg) variant details
- p.Lys102Arg
- TOPMed rs1434786345
- gnomAD rs1434786345
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.08
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available