I137V (p.Ile137Val) variant of MCM6 (Q14566)
I137V (p.Ile137Val) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
I137V (p.Ile137Val) variant details
- p.Ile137Val
- TOPMed rs1002471707
- gnomAD rs1002471707
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.18
- CADD 24.80
- PolyPhen-2 0.47
- SIFT 0.05
- Population evidence available
- Structural context available