I104V (p.Ile104Val) variant of MCM6 (Q14566)
I104V (p.Ile104Val) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I104V (p.Ile104Val) variant details
- p.Ile104Val
- ExAC rs766197896
- TOPMed rs766197896
- gnomAD rs766197896
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.11
- CADD 17.70
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available