I104F (p.Ile104Phe) variant of MCM6 (Q14566)
I104F (p.Ile104Phe) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
I104F (p.Ile104Phe) variant details
- p.Ile104Phe
- ExAC rs766197896
- TOPMed rs766197896
- gnomAD rs766197896
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.13
- CADD 22.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available