H15Q (p.His15Gln) variant of MCM6 (Q14566)
H15Q (p.His15Gln) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H15Q (p.His15Gln) variant details
- p.His15Gln
- TOPMed rs938274968
- gnomAD rs938274968
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.23
- CADD 9.21
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available