H15L (p.His15Leu) variant of MCM6 (Q14566)
H15L (p.His15Leu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
H15L (p.His15Leu) variant details
- p.His15Leu
- gnomAD rs1184767359
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.34
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.73
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available