H148Y (p.His148Tyr) variant of MCM6 (Q14566)
H148Y (p.His148Tyr) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
H148Y (p.His148Tyr) variant details
- p.His148Tyr
- TOPMed rs1276470233
- gnomAD rs1276470233
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.40
- CADD 26.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available