G154R (p.Gly154Arg) variant of MCM6 (Q14566)
G154R (p.Gly154Arg) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G154R (p.Gly154Arg) variant details
- p.Gly154Arg
- ExAC rs767781045
- TOPMed rs767781045
- gnomAD rs767781045
- Missense
- Variant Prioritization Score for Impact Estimate 0.695
- REVEL 0.62
- CADD 27.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available