G132D (p.Gly132Asp) variant of MCM6 (Q14566)
G132D (p.Gly132Asp) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G132D (p.Gly132Asp) variant details
- p.Gly132Asp
- Ensembl rs1680147497
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.53
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available