E81G (p.Glu81Gly) variant of MCM6 (Q14566)
E81G (p.Glu81Gly) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
E81G (p.Glu81Gly) variant details
- p.Glu81Gly
- TOPMed rs752176648
- gnomAD rs752176648
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- REVEL 0.33
- CADD 31.00
- PolyPhen-2 0.57
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available