E36Q (p.Glu36Gln) variant of MCM6 (Q14566)
E36Q (p.Glu36Gln) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
E36Q (p.Glu36Gln) variant details
- p.Glu36Gln
- ExAC rs769402048
- TOPMed rs769402048
- gnomAD rs769402048
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.15
- CADD 25.00
- PolyPhen-2 0.38
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available