E17G (p.Glu17Gly) variant of MCM6 (Q14566)
E17G (p.Glu17Gly) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
E17G (p.Glu17Gly) variant details
- p.Glu17Gly
- TOPMed rs1441410836
- gnomAD rs1441410836
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.06
- CADD 24.00
- PolyPhen-2 0.02
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available