D67E (p.Asp67Glu) variant of MCM6 (Q14566)
D67E (p.Asp67Glu) in MCM6 (Q14566) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D67E (p.Asp67Glu) variant details
- p.Asp67Glu
- ExAC rs750109785
- TOPMed rs750109785
- gnomAD rs750109785
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.13
- CADD 19.50
- PolyPhen-2 0.12
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available